Abstract
The pancreatic carcinogen DHPN (dihydroxypropylnitrosamin) was administered to Syrian golden hamsters. By intragastric administration more pancreatic carcinomas in the head of the gland were induced than by subcutaneous injections. After choledochojejunostomy the incidence of carcinomas was only 5 - 7% and the lesions were similar in multiplicity and distribution without relationship to the way of administration. The importance of biliary reflux in pancreatic tumor induction is discussed and the role of bile concerning the preferred localisation of the tumors in the head of the pancreas.
| Translated title of the contribution | Experimental induced pancreatic carcinoma after choledochojejunostomy |
|---|---|
| Original language | German |
| Pages (from-to) | 261-268 |
| Number of pages | 8 |
| Journal | Langenbecks Archiv für Chirurgie |
| Volume | 348 |
| Issue number | 4 |
| DOIs | |
| State | Published - Dec 1979 |
| Externally published | Yes |