TY - JOUR
T1 - Experimental fluorescence tomography of tissues with noncontact measurements
AU - Schulz, Ralf B.
AU - Ripoll, Jorge
AU - Ntziachristos, Vasilis
PY - 2004/4
Y1 - 2004/4
N2 - Noncontact optical measurements from diffuse media could facilitate the use of large detector arrays at multiple angles that are well suited for diffuse optical tomography applications. Such imaging strategy could eliminate the need for individual fibers in contact with tissue, restricted geometries, and matching fluids. Thus, it could significantly improve experimental procedures and enhance our ability to visualize functional and molecular processes in vivo. In this paper, we describe the experimental implementation of this novel concept and demonstrate capacity to perform small animal imaging.
AB - Noncontact optical measurements from diffuse media could facilitate the use of large detector arrays at multiple angles that are well suited for diffuse optical tomography applications. Such imaging strategy could eliminate the need for individual fibers in contact with tissue, restricted geometries, and matching fluids. Thus, it could significantly improve experimental procedures and enhance our ability to visualize functional and molecular processes in vivo. In this paper, we describe the experimental implementation of this novel concept and demonstrate capacity to perform small animal imaging.
KW - Biomedical imaging
KW - Optical fluorescence tomography
UR - http://www.scopus.com/inward/record.url?scp=1942454913&partnerID=8YFLogxK
U2 - 10.1109/TMI.2004.825633
DO - 10.1109/TMI.2004.825633
M3 - Article
C2 - 15084074
AN - SCOPUS:1942454913
SN - 0278-0062
VL - 23
SP - 492
EP - 500
JO - IEEE Transactions on Medical Imaging
JF - IEEE Transactions on Medical Imaging
IS - 4
ER -