Exhalation of ethylene oxide by rats on exposure to ethylene

J. G. Filser, H. M. Bolt

Research output: Contribution to journalArticlepeer-review

52 Scopus citations

Abstract

When rats are exposed to ethylene in a closed desiccator jar chamber, the rate of metabolic elimination of the compound is influenced by pretreatment with Aroclor 1254 (metabolism increased) and diethyldithiocarbamate (metabolism inhibited). Biotransformation of ethylene leads to ethylene oxide as reactive intermediate. This is exhaled and can be quantitated in the gas phase of the system.

Original languageEnglish
Pages (from-to)57-60
Number of pages4
JournalMutation Research Letters
Volume120
Issue number1
DOIs
StatePublished - Apr 1983
Externally publishedYes

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