Abstract
When rats are exposed to ethylene in a closed desiccator jar chamber, the rate of metabolic elimination of the compound is influenced by pretreatment with Aroclor 1254 (metabolism increased) and diethyldithiocarbamate (metabolism inhibited). Biotransformation of ethylene leads to ethylene oxide as reactive intermediate. This is exhaled and can be quantitated in the gas phase of the system.
Original language | English |
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Pages (from-to) | 57-60 |
Number of pages | 4 |
Journal | Mutation Research Letters |
Volume | 120 |
Issue number | 1 |
DOIs | |
State | Published - Apr 1983 |
Externally published | Yes |