Exhalation of acetone by rats on exposure to trans-1,2-dichloroethylene and related compounds

J. G. Filser, H. M. Bolt, K. Kimmich, F. A. Bencsáth

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

If rats are exposed in a closed system to trans-1,2-dichloroethylene (900 ppm initial concentration), acetone is exhaled at a rate of 1.95 ± 0.79 (SD) μmol h per kg body weight. Acetone exhalation may reflect metabolic changes induced by the xenobiotic, and can also be elicited by exposure to cis-1,2-dichloroethylene, perchloroethylene and vinylidene fluoride.

Original languageEnglish
Pages (from-to)247-252
Number of pages6
JournalToxicology Letters
Volume2
Issue number4
DOIs
StatePublished - Oct 1978
Externally publishedYes

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