Excited-state controlled peroxide formation of DNA

Harun Parlar

doi:10.1016/0147-6513(85)90013-2

Excited-state controlled peroxide formation of DNA

Harun Parlar

Chair of Food Chemistry and Molecular Sensory Science

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Reactions with water and 2 + 2-cycloadditions of individual bases are the primary steps held responsible for the deformation of DNA at short wavelengths. From the observed data however the influence of atmospheric oxygen on the light-induced reaction of DNA is evident. A plausible explanation for these effects is the formation of reactive oxygen species during the UV irradiation of DNA. In the present work the deformation of DNA by different oxygen species like singlet oxygen (¹O₂), superoxideanion (O₂), hydroxyradical (OH^•), and ozone (O₃) is excluded with the help of chemical-trapping experiments. The photoinduced transformation proceeds via excited states of DNA, which react with oxygen to afford peroxide.

Original language	English
Pages (from-to)	120-127
Number of pages	8
Journal	Ecotoxicology and Environmental Safety
Volume	10
Issue number	1
DOIs	https://doi.org/10.1016/0147-6513(85)90013-2
State	Published - Aug 1985

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/0147-6513(85)90013-2

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title = "Excited-state controlled peroxide formation of DNA",

abstract = "Reactions with water and 2 + 2-cycloadditions of individual bases are the primary steps held responsible for the deformation of DNA at short wavelengths. From the observed data however the influence of atmospheric oxygen on the light-induced reaction of DNA is evident. A plausible explanation for these effects is the formation of reactive oxygen species during the UV irradiation of DNA. In the present work the deformation of DNA by different oxygen species like singlet oxygen (1O2), superoxideanion (O2), hydroxyradical (OH•), and ozone (O3) is excluded with the help of chemical-trapping experiments. The photoinduced transformation proceeds via excited states of DNA, which react with oxygen to afford peroxide.",

author = "Harun Parlar",

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AB - Reactions with water and 2 + 2-cycloadditions of individual bases are the primary steps held responsible for the deformation of DNA at short wavelengths. From the observed data however the influence of atmospheric oxygen on the light-induced reaction of DNA is evident. A plausible explanation for these effects is the formation of reactive oxygen species during the UV irradiation of DNA. In the present work the deformation of DNA by different oxygen species like singlet oxygen (1O2), superoxideanion (O2), hydroxyradical (OH•), and ozone (O3) is excluded with the help of chemical-trapping experiments. The photoinduced transformation proceeds via excited states of DNA, which react with oxygen to afford peroxide.

UR - https://www.scopus.com/pages/publications/0021968991

U2 - 10.1016/0147-6513(85)90013-2

DO - 10.1016/0147-6513(85)90013-2

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SP - 120

EP - 127

JO - Ecotoxicology and Environmental Safety

JF - Ecotoxicology and Environmental Safety

IS - 1

ER -

Excited-state controlled peroxide formation of DNA

Abstract

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