Excellent correlation between cathepsin B inhibition and cytotoxicity for a series of palladacycles

Keyphrases

• Cytotoxicity 100%
• Phenyl 100%
• Benzo 100%
• 1-Methyl 100%
• Palladacycle 100%
• Cathepsin B Inhibitors 100%
• Diazepin 100%
• Isopropyl 40%
• Dppe 40%
• Dppf 40%
• In Vitro Activity 20%
• Single Crystal 20%
• Methyl 20%
• Dimethyl 20%
• X-ray Crystallography 20%
• Solid State 20%
• Six-membered 20%
• Benzyl 20%
• Five-membered 20%
• 1,2-Bis(4-pyridyl)ethane 20%
• 31P NMR Spectroscopy 20%
• 1H NMR Spectroscopy 20%
• PdCl2 20%
• Cancer-related 20%
• Dimeric Complex 20%
• A2780 20%
• 1,3,5-Triaza-7-phosphaadamantane 20%
• Cytotoxic Agents 20%
• Monomeric Complex 20%
• SCell 20%
• 1,1'-bis(diphenylphosphino)ferrocene 20%
• Sulfanes 20%

Chemistry

• Diazepam 100%
• 1H NMR Spectroscopy 20%
• Ferrocene 20%
• Single Crystalline Solid 20%
• Phosphorus-31 Magnetic Resonance Spectroscopy 20%
• 1,2-bis(diphenylphosphino)ethane 20%
• Cathepsin B Inhibitor 20%
• X-Ray Crystallography 20%
• Cytotoxic Agent 20%