Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4

Nancy Terryn; Leo Heijnen; Annick De Keyser; Martien Van Asseldonck; Rebecca De Clercq; Henk Verbakel; Jan Gielen; Marc Zabeau; Raimundo Villarroel; Taco Jesse; Pia Neyt; René Hogers; Hilde Van Den Daele; Wilson Ardiles; Christine Schueller; Klaus Mayer; Patrice Déhais; Stephane Rombauts; Marc Van Montagu; Pierre Rouzé; Pieter Vos

doi:10.1016/S0014-5793(99)00097-6

Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4

Nancy Terryn, Leo Heijnen, Annick De Keyser, Martien Van Asseldonck, Rebecca De Clercq, Henk Verbakel, Jan Gielen, Marc Zabeau, Raimundo Villarroel, Taco Jesse, Pia Neyt, René Hogers, Hilde Van Den Daele, Wilson Ardiles, Christine Schueller, Klaus Mayer, Patrice Déhais, Stephane Rombauts, Marc Van Montagu, Pierre RouzéPieter Vos

Research output: Contribution to journal › Article › peer-review

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Abstract

As part of the European Scientists Sequencing Arabidopsis program, a contiguous region (396 607 bp) located on chromosome 4 around the APETALA2 gene was sequenced. Analysis of the sequence and comparison to public databases predicts 103 genes in this area, which represents a gene density of one gene per 3.85 kb. Almost half of the genes show no significant homology to known database entries. In addition, the first 45 kb of the contig, which covers 11 genes, is similar to a region on chromosome 2, as far as coding sequences are concerned. This observation indicates that ancient duplications of large pieces of DNA have occurred in Arabidopsis. Copyright (C) 1999 Federation of European Biochemical Societies.

Original language	English
Pages (from-to)	237-245
Number of pages	9
Journal	FEBS Letters
Volume	445
Issue number	2-3
DOIs	https://doi.org/10.1016/S0014-5793(99)00097-6
State	Published - 26 Feb 1999
Externally published	Yes

Keywords

APETALA2
Arabidopsis thaliana
Genome
Sequencing

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Terryn, N., Heijnen, L., De Keyser, A., Van Asseldonck, M., De Clercq, R., Verbakel, H., Gielen, J., Zabeau, M., Villarroel, R., Jesse, T., Neyt, P., Hogers, R., Van Den Daele, H., Ardiles, W., Schueller, C., Mayer, K., Déhais, P., Rombauts, S., Van Montagu, M., ... Vos, P. (1999). Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4. FEBS Letters, 445(2-3), 237-245. https://doi.org/10.1016/S0014-5793(99)00097-6

@article{d7d6c029fa244e86881fb9e527b719cc,

title = "Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4",

abstract = "As part of the European Scientists Sequencing Arabidopsis program, a contiguous region (396 607 bp) located on chromosome 4 around the APETALA2 gene was sequenced. Analysis of the sequence and comparison to public databases predicts 103 genes in this area, which represents a gene density of one gene per 3.85 kb. Almost half of the genes show no significant homology to known database entries. In addition, the first 45 kb of the contig, which covers 11 genes, is similar to a region on chromosome 2, as far as coding sequences are concerned. This observation indicates that ancient duplications of large pieces of DNA have occurred in Arabidopsis. Copyright (C) 1999 Federation of European Biochemical Societies.",

keywords = "APETALA2, Arabidopsis thaliana, Genome, Sequencing",

author = "Nancy Terryn and Leo Heijnen and {De Keyser}, Annick and {Van Asseldonck}, Martien and {De Clercq}, Rebecca and Henk Verbakel and Jan Gielen and Marc Zabeau and Raimundo Villarroel and Taco Jesse and Pia Neyt and Ren{\'e} Hogers and {Van Den Daele}, Hilde and Wilson Ardiles and Christine Schueller and Klaus Mayer and Patrice D{\'e}hais and Stephane Rombauts and {Van Montagu}, Marc and Pierre Rouz{\'e} and Pieter Vos",

note = "Funding Information: The authors wish to acknowledge the ABRC Stock Center in Ohio for the distribution of ESTs, M. Bevan for coordinating the ESSA program, H.W. Mewes, S. Klostermann, and N. Chalwatzis from MIPS for computer data analysis, Peter Breyne and Koen Goethals for critical reading of the manuscript, M. De Cock for help preparing it, and Rebecca Verbanck for the figures. This work was supported by the EU (Biotech ERBB102-CT93-0075 and ERBB104-CT96-0338) and by the Flemish government (VLAB-COT). ",

year = "1999",

month = feb,

day = "26",

doi = "10.1016/S0014-5793(99)00097-6",

language = "English",

volume = "445",

pages = "237--245",

journal = "FEBS Letters",

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Terryn, N, Heijnen, L, De Keyser, A, Van Asseldonck, M, De Clercq, R, Verbakel, H, Gielen, J, Zabeau, M, Villarroel, R, Jesse, T, Neyt, P, Hogers, R, Van Den Daele, H, Ardiles, W, Schueller, C, Mayer, K, Déhais, P, Rombauts, S, Van Montagu, M, Rouzé, P & Vos, P 1999, 'Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4', FEBS Letters, vol. 445, no. 2-3, pp. 237-245. https://doi.org/10.1016/S0014-5793(99)00097-6

TY - JOUR

T1 - Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4

AU - Terryn, Nancy

AU - Heijnen, Leo

AU - De Keyser, Annick

AU - Van Asseldonck, Martien

AU - De Clercq, Rebecca

AU - Verbakel, Henk

AU - Gielen, Jan

AU - Zabeau, Marc

AU - Villarroel, Raimundo

AU - Jesse, Taco

AU - Neyt, Pia

AU - Hogers, René

AU - Van Den Daele, Hilde

AU - Ardiles, Wilson

AU - Schueller, Christine

AU - Mayer, Klaus

AU - Déhais, Patrice

AU - Rombauts, Stephane

AU - Van Montagu, Marc

AU - Rouzé, Pierre

AU - Vos, Pieter

N1 - Funding Information: The authors wish to acknowledge the ABRC Stock Center in Ohio for the distribution of ESTs, M. Bevan for coordinating the ESSA program, H.W. Mewes, S. Klostermann, and N. Chalwatzis from MIPS for computer data analysis, Peter Breyne and Koen Goethals for critical reading of the manuscript, M. De Cock for help preparing it, and Rebecca Verbanck for the figures. This work was supported by the EU (Biotech ERBB102-CT93-0075 and ERBB104-CT96-0338) and by the Flemish government (VLAB-COT).

PY - 1999/2/26

Y1 - 1999/2/26

N2 - As part of the European Scientists Sequencing Arabidopsis program, a contiguous region (396 607 bp) located on chromosome 4 around the APETALA2 gene was sequenced. Analysis of the sequence and comparison to public databases predicts 103 genes in this area, which represents a gene density of one gene per 3.85 kb. Almost half of the genes show no significant homology to known database entries. In addition, the first 45 kb of the contig, which covers 11 genes, is similar to a region on chromosome 2, as far as coding sequences are concerned. This observation indicates that ancient duplications of large pieces of DNA have occurred in Arabidopsis. Copyright (C) 1999 Federation of European Biochemical Societies.

AB - As part of the European Scientists Sequencing Arabidopsis program, a contiguous region (396 607 bp) located on chromosome 4 around the APETALA2 gene was sequenced. Analysis of the sequence and comparison to public databases predicts 103 genes in this area, which represents a gene density of one gene per 3.85 kb. Almost half of the genes show no significant homology to known database entries. In addition, the first 45 kb of the contig, which covers 11 genes, is similar to a region on chromosome 2, as far as coding sequences are concerned. This observation indicates that ancient duplications of large pieces of DNA have occurred in Arabidopsis. Copyright (C) 1999 Federation of European Biochemical Societies.

KW - APETALA2

KW - Arabidopsis thaliana

KW - Genome

KW - Sequencing

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U2 - 10.1016/S0014-5793(99)00097-6

DO - 10.1016/S0014-5793(99)00097-6

M3 - Article

C2 - 10094464

AN - SCOPUS:0032979838

SN - 0014-5793

VL - 445

SP - 237

EP - 245

JO - FEBS Letters

JF - FEBS Letters

IS - 2-3

ER -

Evidence for an ancient chromosomal duplication in Arabidopsis thaliana by sequencing and analyzing a 400-kb contig at the APETALA2 locus on chromosome 4

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Keywords

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