TY - JOUR
T1 - Evaluation of new software for angiographic determination of right ventricular volumes
AU - Wellnhofer, Ernst
AU - Ewert, Peter
AU - Hug, Jürgen
AU - Hui, Wei
AU - Kretschmar, Oliver
AU - Chavengsuk, Disthapron
AU - Kühne, Titus
AU - Abdul-Khaliq, Hashim
AU - Nagel, Eike
AU - Lange, Peter E.
AU - Fleck, Eckart
N1 - Funding Information:
This study was supported by Pie Medical Imaging B.V. 6216 BX Maastricht, The Netherlands. We want to express our special thanks to Guus Kroes (Pie Medical Imaging B.V) and Mr Uwe Kokartis (Deutsches Herzzentrum Berlin).
PY - 2005/12
Y1 - 2005/12
N2 - Objectives: The scope of the study was to evaluate a recent software for angiographic volume determination as compared to cardiovascular magnetic resonance imaging. Background: A new right ventricular analysis software closes a diagnostic gap in quantitative angiography. Cardiovascular magnetic resonance imaging short axis multi slice summation is a validated reference standard. Methods: Right ventricular angiograms were acquired in frontal and lateral projection in 15 pediatric and 17 adult patients. Additional angiograms were acquired in RAO30°/LAO60° projections in 10 adult patients. The tested models comprised area length with different regressions, multi-slice with different regressions, Boak, and pyramid method. Original regressions were used to calculate angiographic right ventricular volume. Right ventricular reference volumes were determined by multi-slice summation from cardiac magnetic resonance short-axis images. Results: Mean inter-observer difference was -1 ml (95% confiden ce: -35-34 ml) and mean intra-observer difference was 0 ml (95% confidence: -22-22 ml). There was no significant difference (4 ml, 95% confidence: -22-30 ml) between geometric calibration and calibration by a sphere. The area length and multi-slice models demonstrated the best agreement with the cardiac magnetic resonance reference. Performance was best for the Onnasch Lange models. Conclusion: The evaluated software provides acceptably accurate volume estimates for the majority of ventricles. In a few cases larger errors may occur, however. The area length and multi-slice models preferably with Onnasch Lange regressions may be recommended. Inter- and intra-observer agreement were excellent. Geometric calibration using data from DICOM header files may be used.
AB - Objectives: The scope of the study was to evaluate a recent software for angiographic volume determination as compared to cardiovascular magnetic resonance imaging. Background: A new right ventricular analysis software closes a diagnostic gap in quantitative angiography. Cardiovascular magnetic resonance imaging short axis multi slice summation is a validated reference standard. Methods: Right ventricular angiograms were acquired in frontal and lateral projection in 15 pediatric and 17 adult patients. Additional angiograms were acquired in RAO30°/LAO60° projections in 10 adult patients. The tested models comprised area length with different regressions, multi-slice with different regressions, Boak, and pyramid method. Original regressions were used to calculate angiographic right ventricular volume. Right ventricular reference volumes were determined by multi-slice summation from cardiac magnetic resonance short-axis images. Results: Mean inter-observer difference was -1 ml (95% confiden ce: -35-34 ml) and mean intra-observer difference was 0 ml (95% confidence: -22-22 ml). There was no significant difference (4 ml, 95% confidence: -22-30 ml) between geometric calibration and calibration by a sphere. The area length and multi-slice models demonstrated the best agreement with the cardiac magnetic resonance reference. Performance was best for the Onnasch Lange models. Conclusion: The evaluated software provides acceptably accurate volume estimates for the majority of ventricles. In a few cases larger errors may occur, however. The area length and multi-slice models preferably with Onnasch Lange regressions may be recommended. Inter- and intra-observer agreement were excellent. Geometric calibration using data from DICOM header files may be used.
KW - Angiography
KW - Cardiac magnetic resonance imaging
KW - Right ventricular volumes
UR - http://www.scopus.com/inward/record.url?scp=30344431781&partnerID=8YFLogxK
U2 - 10.1007/s10554-005-1797-7
DO - 10.1007/s10554-005-1797-7
M3 - Article
C2 - 16322915
AN - SCOPUS:30344431781
SN - 1569-5794
VL - 21
SP - 575
EP - 585
JO - International Journal of Cardiovascular Imaging
JF - International Journal of Cardiovascular Imaging
IS - 6
ER -