Evaluation of Fe and Ru Pincer-Type Complexes as Catalysts for the Racemization of Secondary Benzylic Alcohols

Christoph Bornschein, Karl P.J. Gustafson, Oscar Verho, Matthias Beller, Jan E. Bäckvall

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Fe and Ru pincer-type catalysts are used for the racemization of benzylic alcohols. Racemization with the Fe catalyst was achieved within 30 minutes under mild reaction conditions, with a catalyst loading as low as 2 mol %. This reaction constitutes the first example of an iron-catalyzed racemization of an alcohol. The efficiency for racemization of the Fe catalyst and its Ru analogue was evaluated for a wide range of sec-benzylic alcohols. The commercially available Ru complex proved to be highly robust and even tolerated the presence of water in the reaction mixture.

Original languageEnglish
Pages (from-to)11583-11586
Number of pages4
JournalChemistry - A European Journal
Volume22
Issue number33
DOIs
StatePublished - 8 Aug 2016
Externally publishedYes

Keywords

  • iron
  • pincer ligands
  • racemization
  • ruthenium
  • secondary alcohols

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