Evaluation des Therapieerfolges bei Kontaktgranulomen

Translated title of the contribution: Evaluation of treatment modalities for contact granulomas

Adrienne Heyduck, Anja Pickhard, Thomas Karl Hoffmann, Sibylle Brosch, Rudolf Reiter

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Introduction There are merely heterogenous therapy modalities for contact granulomas (CG) without evidenced efficacy. The intention of our study was to evaluate possible risk factors as well as to demonstrate therapeutic successful approaches. Methods Based on a retrospective analysis on 79 patients with CG we evaluated personal data for the first patient contact, for the first follow-up appointment (FA) averaged 3-4 months after the first contact, for the second follow-up appointment (SA) averaged 6-8 months after the first contact and for the last follow-up (LA) averaged 13 months after the first contact with collecting information concerning a possible gastrolaryngeal reflux disease as well as symptoms like harrumphing, hoarseness, hyperfunctional dysphonia as well as videostroboscopic signs. The therapeutic methods were prohibition of harrumphing, speech therapy, antazida therapy, surgical resection or a combination of therapy modalities. The group of FA and SA were divided into groups of complete remission group and incomplete remission group, symptoms and stroboscopic signs were statistically compared. Results Harrumphing was an important cofactor in developing a CG. Although we couldn't verify a superior therapy modality a complete remission was archieved in 2/3rd of the reviewed cases. Even if there was an incomplete remission of the contact granuloma we were able to show a reduction of symptoms. Surgical resections of CG showed a significantly higher recurrence rate. Discussion Even if we couldn't confirm a superior therapy modality we recommend a symptomatic therapy of CG with overall good remission rates. Primary surgical interventions are not advised owing to high recurrence rates.

Translated title of the contributionEvaluation of treatment modalities for contact granulomas
Original languageGerman
Pages (from-to)555-561
Number of pages7
JournalLaryngo- Rhino- Otologie
Volume98
Issue number8
DOIs
StatePublished - 2019

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