TY - JOUR
T1 - Estrogenic effects from household stoves
AU - Wu, W. Z.
AU - Chen, J.
AU - Rehmann, K.
AU - Schramm, K. W.
AU - Kettrup,
PY - 2002/9
Y1 - 2002/9
N2 - With the application of a genetically modified yeast, estrogen receptor-activating compounds were detected in the soot and emission gas of a wood-burning household stove. The EC50 value of 17β-estradiol was divided by the EC50 value of soot, and the obtained relative estrogenic value for raw soot was 2.37E-5, indicating that soot was about 100,000 times less estrogenic than 17β-estradiol. Chemical analysis revealed that alkyl phenol, benzonic acid, and PAHs represented the major constituents in the most potent fractions of the soot. Along with PAHs, other constituents might also contribute to the estrogenicity of soot.
AB - With the application of a genetically modified yeast, estrogen receptor-activating compounds were detected in the soot and emission gas of a wood-burning household stove. The EC50 value of 17β-estradiol was divided by the EC50 value of soot, and the obtained relative estrogenic value for raw soot was 2.37E-5, indicating that soot was about 100,000 times less estrogenic than 17β-estradiol. Chemical analysis revealed that alkyl phenol, benzonic acid, and PAHs represented the major constituents in the most potent fractions of the soot. Along with PAHs, other constituents might also contribute to the estrogenicity of soot.
UR - http://www.scopus.com/inward/record.url?scp=0036735025&partnerID=8YFLogxK
U2 - 10.1006/eesa.2002.2192
DO - 10.1006/eesa.2002.2192
M3 - Article
C2 - 12481859
AN - SCOPUS:0036735025
SN - 0147-6513
VL - 53
SP - 65
EP - 69
JO - Ecotoxicology and Environmental Safety
JF - Ecotoxicology and Environmental Safety
IS - 1
ER -
