Escherichia coli DNA synthesis in vitro: Insensitivity of ATP-dependent DNA repair to inhibition by novobiocin

Peter K. Schneck, Walter L. Staudenbauer

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

Novobiocin, an effective inhibitor of DNA replication in Escherichia coli, is shown to have no effect on the ATP-dependent DNA repair carried out by toluenized cells after ultraviolet irradiation. Therefore novobiocin can be considered a selective inhibitor of replicative DNA synthesis in vitro.

Original languageEnglish
Pages (from-to)2057-2064
Number of pages8
JournalNucleic Acids Research
Volume4
Issue number6
DOIs
StatePublished - Jun 1977
Externally publishedYes

Fingerprint

Dive into the research topics of 'Escherichia coli DNA synthesis in vitro: Insensitivity of ATP-dependent DNA repair to inhibition by novobiocin'. Together they form a unique fingerprint.

Cite this