Erratum: Inference of past demography, dormancy and self-fertilization rates from whole genome sequence data I(PLoS Genet (2020) 16:4 (e1008698) DOI: 10.1371/journal.pgen.1008698)

Thibaut Paul Patrick Sellinger, Diala Abu Awad, Markus Moest, Aurélien Tellier

Research output: Contribution to journalComment/debate

Abstract

The mutation and recombination rates reported throughout the article are incorrect by a factor of 2. The captions of Figs 1–4, Table 2, and S1–S19 Figs are incorrect. Additionally, the Y axes of Figs 5 and 6 and S20 Fig are shifted by a factor of 2. The authors provide corrected versions here. The correct rates were used for the simulations (S2 Appendix) and as such this error does not affect the conclusions of the study. There are several errors in the Simulation results subsection of the Results as listed below. In the Convergence property in the absence of seed-banks and self-fertilization subheading, there are errors in the first sentence of the fourth paragraph. The correct sentence is: We now assume ry ¼ mr ¼ 5, with the mutation and recombination rate respectively set to 1.25 × 108 and 6.25 × 10−8 per generation per nucleotide. In the Convergence property with dormancy (seed- or egg-banks) subheading of the Simulation results subsection of the Results, there is an error in the first sentence of the first paragraph. The correct sentence is: Using eSMC on sequences simulated under the “saw-tooth” scenario in the presence of seed-banks (mutation and recombination rates are set to 1.25 × 10−8 per generation per bp, (Fig 2), we obtain an accurate estimation of the demography (χt) and of the germination rates (β). There is also an error in the last sentence of the first paragraph. The correct sentence is: Therefore when the molecular mutation and recombination are set to 2.5 × 10−9 per generation per bp, better fits are obtained (S12 Fig). In the Convergence property with dormancy (seed- or egg-banks) subheading, there are several errors in the second paragraph. The correct paragraph is: For simpler demographic scenarios (constant population size, bottleneck, expansion and decrease, see S13 Fig) and μ = r = 1.25 × 10−8 per generation per bp, the germination rate and the demographic histories estimated by eSMC are accurate for most of the demographic scenarios considered, except in the case of a bottleneck scenario (as expected from previous results). In presence of strong seed-banks (β = 0.2 or 0.1) there are biases in estimations of the far past. Once again, this tendency disappears when the molecular mutation and recombination rates per site are lowered so as not to violate the infinite site model (μ and r = 2.5 × 10−9 per generation per bp, see S14 Fig). In the Convergence property with self-fertilization subheading, there is an error in the first sentence of the first paragraph. The correct sentence is: Under the “saw-tooth” scenario with different rates of self-fertilization σ, with mutation and recombination rates set to 1.25 × 108 per generation per bp (mr ¼ 1), for four different self-fertilization rates σ = 0 (no self-fertilization), 0.5 (50% selfing), 0.8 (80% selfing) and 0.9 (90% selfing), we estimate the self-fertilization rate respectively at 0.19, 0.5, 0.77 and 0.87 (Fig 3). There are also errors in the fifth sentence of the first paragraph. The correct sentence is: When the mutation rate is set to 1.25 × 10−8 per generation per bp and the recombination rate to 6.25 × 10−8 per generation per nucleotide (mr ¼ 5), the self-fertilization rate is overestimated for small values of σ (S15 Fig), but well estimated for higher values of σ. In the Convergence property with both dormancy and self-fertilization subheading, there is an error in the first sentence of the first paragraph. The correct sentence is: Here we test different combinations of seed/egg-banks and self-fertilization rates that result in the same ratio ry ¼ 0:15, with mr ¼ 1 (setting μ = r = 1.25 × 10−8 per generation per bp). There is also an error in the eleventh sentence of the first paragraph. The correct sentence is: We also test how recombination can influence the output of these models, notably by taking a higher recombination rate (8.335 × 10−8 per site per generation), more representative of the high recombination to mutation ratio observed in some species (notably D. pulex and A. thaliana [4, 45]).

Original languageEnglish
Article numbere1009504
JournalPLoS Genetics
Volume17
Issue number4
DOIs
StatePublished - 7 Apr 2021

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