Enriching the interventional vision of cancer with fluorescence and optoacoustic imaging

P. Beatriz Garcia-Allende, Jürgen Glatz, Maximilian Koch, Vasilis Ntziachristos

Research output: Contribution to journalReview articlepeer-review

24 Scopus citations


Among several techniques considered for surgical and endoscopic imaging, novel optical methods are evolving as a promising approach for interventional guidance. Pilot clinical applications of fluorescence molecular imaging have demonstrated the benefits of using targeted fluorescent agents in cancer surgery. This premise can be extended broadly to interventional guidance through an increasing number of targeted agents and detection techniques. Beyond epi-illumination fluorescence imaging, optoacoustic (photoacoustic) methods are emerging to offer high-resolution cross-sectional optical imaging through several millimeters to centimeters of depth. We present an overview of key recent developments in optical interventional imaging and outline the potential for a paradigm shift in surgical and endoscopic visualization.

Original languageEnglish
Pages (from-to)664-667
Number of pages4
JournalJournal of Nuclear Medicine
Issue number5
StatePublished - 1 May 2013


  • Endoscopy
  • Fluorescence molecular imaging
  • Fluorescent agents
  • Optoacoustic imaging
  • Photoacoustic imaging
  • Surgery


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