Endocrine tumors of the gut and pancreas tumor biology and classification

G. Rindi, G. Klöppel

Research output: Contribution to journalArticlepeer-review

92 Scopus citations

Abstract

The endocrine tumors of the gut and pancreas tract are a group of neoplasms composed of cells with a neuroendocrine phenotype. Well-differentiated tumors, well-differentiated carcinomas and poorly differentiated carcinomas are the major categories identified. According to their localization (stomach, duodenum-jejunum, ileum, appendix and colorectum), they display distinct phenotypes, regarding their pathology, immunohistochemistry and hormonal syndromes. Their clinical behavior spans from benign, uncertain malignant potential, low-grade malignant to high-grade malignant. Currently, extensive work is performed to unravel the genetic background.

Original languageEnglish
Pages (from-to)12-15
Number of pages4
JournalNeuroendocrinology
Volume80
Issue numberSUPPL. 1
DOIs
StatePublished - 2004
Externally publishedYes

Keywords

  • Endocrine cells
  • Endocrine tumors
  • Genetics
  • Gut
  • Hormones
  • Immunohistochemistry
  • Neuroendocrine markers
  • Pancreas

Fingerprint

Dive into the research topics of 'Endocrine tumors of the gut and pancreas tumor biology and classification'. Together they form a unique fingerprint.

Cite this