Abstract
The endocrine tumors of the gut and pancreas tract are a group of neoplasms composed of cells with a neuroendocrine phenotype. Well-differentiated tumors, well-differentiated carcinomas and poorly differentiated carcinomas are the major categories identified. According to their localization (stomach, duodenum-jejunum, ileum, appendix and colorectum), they display distinct phenotypes, regarding their pathology, immunohistochemistry and hormonal syndromes. Their clinical behavior spans from benign, uncertain malignant potential, low-grade malignant to high-grade malignant. Currently, extensive work is performed to unravel the genetic background.
Original language | English |
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Pages (from-to) | 12-15 |
Number of pages | 4 |
Journal | Neuroendocrinology |
Volume | 80 |
Issue number | SUPPL. 1 |
DOIs | |
State | Published - 2004 |
Externally published | Yes |
Keywords
- Endocrine cells
- Endocrine tumors
- Genetics
- Gut
- Hormones
- Immunohistochemistry
- Neuroendocrine markers
- Pancreas