Enantioselective reduction of prochiral ketones by engineered bifunctional fusion proteins

Keyphrases

• Fusion Protein 100%
• Prochiral Ketones 100%
• Enantioselective Reduction 100%
• Bifunctional Fusion Protein 100%
• Oxidoreductase 66%
• Formate Dehydrogenase 66%
• Ethanol 33%
• Enzymatic Activity 33%
• Pentafluorophenyl 33%
• Linker 33%
• Reduction Reaction 33%
• Chiral Alcohols 33%
• Escherichia Coli Cells 33%
• Enantiomeric Excess 33%
• Nicotinamide Adenine Dinucleotide Phosphate (NADPH) 33%
• Nicotinamide Cofactor 33%
• Acyl Carrier Protein 33%
• NADP+ 33%
• Reductase 33%
• Synechococcus 33%
• Insertion mutation 33%
• Cofactor Regeneration 33%
• Frame Fusion 33%
• Substrate Conversion 33%
• In Situ Regeneration 33%
• Mycobacterium Vaccae 33%
• Whole Cell Bioreduction 33%
• PCC 7942 33%
• Initial Reaction Rate 33%
• Chiral Synthons 33%

Biochemistry, Genetics and Molecular Biology

• Chimeric Protein 100%
• Oxidoreductase 60%
• Enzyme 40%
• Formate Dehydrogenase 40%
• Reductase 20%
• Escherichia coli 20%
• Enzyme Activity 20%
• Acyl Carrier Protein 20%
• Synechococcus 20%
• Mycobacterium vaccae 20%
• Whole Cell 20%
• Nicotinamide Adenine Dinucleotide Phosphate 20%
• Nicotinamide 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Chimeric Protein 100%
• Oxidoreductase 40%
• Formate Dehydrogenase 40%
• 3 Oxoacyl Acyl Carrier Protein Reductase 20%
• Escherichia coli 20%
• Alcohol Derivative 20%
• Reduced Nicotinamide Adenine Dinucleotide Phosphate 20%
• Mycobacterium vaccae 20%
• Synechococcus 20%
• Nicotinamide 20%
• Nicotinamide Adenine Dinucleotide Phosphate 20%