Abstract
Background: The debate on whether sex-specific predictive models improve risk stratification after myocardial infarction is ongoing. Methods: This review summarises the current clinical knowledge on sex-specific differences in post-infarction risk stratification parameters. Particular focus is given to electrocardiographic risk factors and indices of cardiac autonomic status. Results: Differences in the underlying pathophysiology between men and women are known. However, clinical findings often lead to uncertain conclusions for a number of risk predictors including, among others, resting heart rate, heart rate variability, heart rate turbulence, QT interval duration, and QRS-T angle. The review links recent findings in prognostic parameters with successful approaches in sex-specific non-invasive risk stratification. Conclusion: Disparities are described in the current clinical opinions on the relevance of investigated parameters in women and possible directions for further research in the field are given.
Original language | English |
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Pages (from-to) | 3817-3828 |
Number of pages | 12 |
Journal | Current Pharmaceutical Design |
Volume | 22 |
Issue number | 25 |
DOIs | |
State | Published - 1 Jul 2016 |
Keywords
- AMI
- Baroreflex sensitivity
- Heart rate
- Heart rate turbulence
- Heart rate variability
- QRS T-angle
- QT width
- Women