Einfluss von Epstein-Barr Virusgenom auf die Uberlebenszeit von Patienten mit M. Hodgkin.

H. Niedermeyer; C. Fellbaum; M. L. Hansmann; I. Kraus; M. J. Alavaikko; R. Busch; B. Pütz; R. Fischer; H. Höfler

Einfluss von Epstein-Barr Virusgenom auf die Uberlebenszeit von Patienten mit M. Hodgkin.

Translated title of the contribution: Influence of Epstein-Barr virus genome on patient survival in Hodgkin's disease

H. Niedermeyer, C. Fellbaum, M. L. Hansmann, I. Kraus, M. J. Alavaikko, R. Busch, B. Pütz, R. Fischer, H. Höfler

TUM Emeriti of Excellence

Technical University of Munich

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

In the literature EBV is considered a possible etiologic factor for Hodgkin's disease (HD). We investigated 187 cases of HD for the presence of Epstein Barr virus using the polymerase chain reaction (PCR) technique on formalin fixed, paraffin embedded lymph node tissue to clarify the clinical importance of the incidence of this genome. The 187 cases included all subtypes. 66 cases (35.2%) were positive for EBV DNA. The statistical analysis of follow-up data from 130 patients revealed no influence of EBV DNA on survival time. In our investigation detection of EBV DNA by PCR showed no prognostic relevance for patients with HD.

Translated title of the contribution	Influence of Epstein-Barr virus genome on patient survival in Hodgkin's disease
Original language	German
Pages (from-to)	173-176
Number of pages	4
Journal	Verhandlungen der Deutschen Gesellschaft für Pathologie
Volume	76
State	Published - 1992

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title = "Einfluss von Epstein-Barr Virusgenom auf die Uberlebenszeit von Patienten mit M. Hodgkin.",

abstract = "In the literature EBV is considered a possible etiologic factor for Hodgkin's disease (HD). We investigated 187 cases of HD for the presence of Epstein Barr virus using the polymerase chain reaction (PCR) technique on formalin fixed, paraffin embedded lymph node tissue to clarify the clinical importance of the incidence of this genome. The 187 cases included all subtypes. 66 cases (35.2%) were positive for EBV DNA. The statistical analysis of follow-up data from 130 patients revealed no influence of EBV DNA on survival time. In our investigation detection of EBV DNA by PCR showed no prognostic relevance for patients with HD.",

author = "H. Niedermeyer and C. Fellbaum and Hansmann, {M. L.} and I. Kraus and Alavaikko, {M. J.} and R. Busch and B. P{\"u}tz and R. Fischer and H. H{\"o}fler",

year = "1992",

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T1 - Einfluss von Epstein-Barr Virusgenom auf die Uberlebenszeit von Patienten mit M. Hodgkin.

AU - Niedermeyer, H.

AU - Fellbaum, C.

AU - Hansmann, M. L.

AU - Kraus, I.

AU - Alavaikko, M. J.

AU - Busch, R.

AU - Pütz, B.

AU - Fischer, R.

AU - Höfler, H.

PY - 1992

Y1 - 1992

N2 - In the literature EBV is considered a possible etiologic factor for Hodgkin's disease (HD). We investigated 187 cases of HD for the presence of Epstein Barr virus using the polymerase chain reaction (PCR) technique on formalin fixed, paraffin embedded lymph node tissue to clarify the clinical importance of the incidence of this genome. The 187 cases included all subtypes. 66 cases (35.2%) were positive for EBV DNA. The statistical analysis of follow-up data from 130 patients revealed no influence of EBV DNA on survival time. In our investigation detection of EBV DNA by PCR showed no prognostic relevance for patients with HD.

AB - In the literature EBV is considered a possible etiologic factor for Hodgkin's disease (HD). We investigated 187 cases of HD for the presence of Epstein Barr virus using the polymerase chain reaction (PCR) technique on formalin fixed, paraffin embedded lymph node tissue to clarify the clinical importance of the incidence of this genome. The 187 cases included all subtypes. 66 cases (35.2%) were positive for EBV DNA. The statistical analysis of follow-up data from 130 patients revealed no influence of EBV DNA on survival time. In our investigation detection of EBV DNA by PCR showed no prognostic relevance for patients with HD.

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AN - SCOPUS:0027017939

SN - 0070-4113

VL - 76

SP - 173

EP - 176

JO - Verhandlungen der Deutschen Gesellschaft für Pathologie

JF - Verhandlungen der Deutschen Gesellschaft für Pathologie

ER -

Einfluss von Epstein-Barr Virusgenom auf die Uberlebenszeit von Patienten mit M. Hodgkin.

Abstract

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