Efficient transfer hydrogenation of ketones in the presence of ruthenium N-heterocyclic carbene catalysts

Stephan Enthaler, Ralf Jackstell, Bernhard Hagemann, Kathrin Junge, Giulia Erre, Matthias Beller

Research output: Contribution to journalArticlepeer-review

68 Scopus citations

Abstract

Novel ruthenium carbene complexes have been in situ generated and tested for the transfer hydrogenation of ketones. Applying Ru(cod)(methylallyl)2 in the presence of imidazolium salts in 2-propanol and sodium-2-propanolate as base, turnover frequencies up to 346 h-1 have been obtained for reduction of acetophenone. A comparative study involving ruthenium carbene and ruthenium phosphine complexes demonstrated the higher activity of ruthenium carbene complexes.

Original languageEnglish
Pages (from-to)4652-4659
Number of pages8
JournalJournal of Organometallic Chemistry
Volume691
Issue number22
DOIs
StatePublished - 1 Nov 2006
Externally publishedYes

Keywords

  • Homogeneous catalysis
  • Ketones
  • N-heterocyclic carbenes
  • Ruthenium
  • Transfer hydrogenation

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