Efficient and regioselective ruthenium-catalyzed hydro-aminomethylation of olefins

Lipeng Wu, Ivana Fleischer, Ralf Jackstell, Matthias Beller

Research output: Contribution to journalArticlepeer-review

82 Scopus citations

Abstract

An efficient and regioselective ruthenium-catalyzed hydroaminomethlyation of olefins is reported. Key to success is the use of specific 2-phosphino-substituted imidazole ligands and triruthenium dodecacarbonyl as catalyst. Both industrially important aliphatic as well as various functionalized olefins react with primary and secondary amines to give the corresponding secondary and tertiary amines generally in high yields (up to 96%) and excellent regioselectivities (n/iso up to 99:1).

Original languageEnglish
Pages (from-to)3989-3996
Number of pages8
JournalJournal of the American Chemical Society
Volume135
Issue number10
DOIs
StatePublished - 13 Mar 2013
Externally publishedYes

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