Effects of lead deficiency on lipid metabolism

A. M. Reichlmayr-Lais, M. Kirchgeßner

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

The criteria of lipid metabolism in lead deficiency were determined. For this purpose an experiment was performed with Sprague-Dawley rats distributed in depletion and control groups. The depletion rats were fed an extremely low lead content diet (20±5 ppb), whereas the diet for the control animals was supplemented with 800 ppb Pb++. Dependent on generation, depletion influenced triglyceride content in serum and liver, phospholipid and cholesterol content in liver as well as the whole body fat of the offspring. The results indicate that in mothers the absorption of lipids is impaired. Consequently it is possible that the mothers do not excrete enough fat with milk leading to an energetical deficiency and therefore to reduced growth.

Original languageEnglish
Pages (from-to)165-170
Number of pages6
JournalZeitschrift fur Ernahrungswissenschaft
Volume25
Issue number3
DOIs
StatePublished - Sep 1986
Externally publishedYes

Keywords

  • lead depletion
  • lipid metabolism
  • liver phospholipids
  • liver triglycerides
  • serum triglycerides
  • total body lipids

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