TY - JOUR
T1 - EAACI/GA2LEN guideline
T2 - Aspirin provocation tests for diagnosis of aspirin hypersensitivity
AU - Nizankowska-Mogilnicka, E.
AU - Bochenek, G.
AU - Mastalerz, L.
AU - Świerczyńska, M.
AU - Picado, C.
AU - Scadding, G.
AU - Kowalski, M. L.
AU - Setkowicz, M.
AU - Ring, J.
AU - Brockow, K.
AU - Bachert, C.
AU - Wöhrl, S.
AU - Dahlén, B.
AU - Szczeklik, A.
PY - 2007/10
Y1 - 2007/10
N2 - Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common causes of adverse drug reactions. Majority of them are of the hypersensitivity type. The two frequent clinical presentations of aspirin hypersensitivity are: aspirin-induced bronchial asthma/rhinosinusitis (AIA/R) and aspirin-induced urticaria/angioedema (AIU). The decisive diagnosis is based on provocation tests with aspirin, as the in vitro test does not hold diagnostic value as yet. Detailed protocols of oral, bronchial and nasal aspirin provocation tests are presented. Indications, contraindications for the tests, the rules of drug withdrawal and equipment are reviewed. Patient supervision and interpretations of the tests are proposed.
AB - Aspirin and other nonsteroidal anti-inflammatory drugs (NSAIDs) are among the most common causes of adverse drug reactions. Majority of them are of the hypersensitivity type. The two frequent clinical presentations of aspirin hypersensitivity are: aspirin-induced bronchial asthma/rhinosinusitis (AIA/R) and aspirin-induced urticaria/angioedema (AIU). The decisive diagnosis is based on provocation tests with aspirin, as the in vitro test does not hold diagnostic value as yet. Detailed protocols of oral, bronchial and nasal aspirin provocation tests are presented. Indications, contraindications for the tests, the rules of drug withdrawal and equipment are reviewed. Patient supervision and interpretations of the tests are proposed.
KW - Aspirin
KW - Aspirin challenge
KW - Aspirin-induced asthma/rhinitis
KW - Aspirin-induced urticaria
KW - Hypersensitivity
UR - http://www.scopus.com/inward/record.url?scp=34548473304&partnerID=8YFLogxK
U2 - 10.1111/j.1398-9995.2007.01409.x
DO - 10.1111/j.1398-9995.2007.01409.x
M3 - Review article
C2 - 17521312
AN - SCOPUS:34548473304
SN - 0105-4538
VL - 62
SP - 1111
EP - 1118
JO - Allergy: European Journal of Allergy and Clinical Immunology
JF - Allergy: European Journal of Allergy and Clinical Immunology
IS - 10
ER -