Dynamics of specific vesicle-substrate adhesion: From local events to global dynamics

Ellen Reister-Gottfried, Kheya Sengupta, Barbara Lorz, Erich Sackmann, Udo Seifert, Ana Sunčana Smith

Research output: Contribution to journalArticlepeer-review

58 Scopus citations

Abstract

We present a synergistic combination of simulations and experimental data on the dynamics of membrane adhesion. We show that a change in either the density or the strength of the bonds results in very different dynamics. Such behavior is explained by introducing an effective binding affinity that emerges as a result of the competition between the strength of the chemical bonds and the environment defined by the fluctuating membrane.

Original languageEnglish
Article number208103
JournalPhysical Review Letters
Volume101
Issue number20
DOIs
StatePublished - 13 Nov 2008

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