Dynamics of force-induced DNA slippage

Richard A. Neher, Ulrich Gerland

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


The base pairing dynamics of DNA with repetitive sequences, where local strand slippage can create, annihilate and move bulge loops, was discussed. A rich dynamical behavior as a function of an applied shear force was found using an explicit theoretical model. A viscoelastic behavior for periodic DNA with force scales and time that can be programmed into its sequence was predicted. The response of periodic dsDNA to shear forces was found, which was very distinct from that for non-periodic sequences.

Original languageEnglish
Article number198102
Pages (from-to)198102-1-198102-4
JournalPhysical Review Letters
Issue number19
StatePublished - 5 Nov 2004
Externally publishedYes


Dive into the research topics of 'Dynamics of force-induced DNA slippage'. Together they form a unique fingerprint.

Cite this