Abstract
The base pairing dynamics of DNA with repetitive sequences, where local strand slippage can create, annihilate and move bulge loops, was discussed. A rich dynamical behavior as a function of an applied shear force was found using an explicit theoretical model. A viscoelastic behavior for periodic DNA with force scales and time that can be programmed into its sequence was predicted. The response of periodic dsDNA to shear forces was found, which was very distinct from that for non-periodic sequences.
| Original language | English |
|---|---|
| Article number | 198102 |
| Pages (from-to) | 198102-1-198102-4 |
| Journal | Physical Review Letters |
| Volume | 93 |
| Issue number | 19 |
| DOIs | |
| State | Published - 5 Nov 2004 |
| Externally published | Yes |