TY - JOUR
T1 - Dynamical transition of bacteriorhodopsin in purple membranes revealed by neutron scattering
T2 - a relation between structure, dynamics and function
AU - Ferrand, M.
AU - Petry, W.
AU - Dianoux, A. J.
AU - Zaccai, G.
PY - 1993/12/1
Y1 - 1993/12/1
N2 - The internal motions of bacteriorhodopsin, the integral membrane protein in purple membranes of Halobacterium halobium, have been studied by neutron scattering as a function of different external conditions. The internal dynamics exhibit a transition above a critical temperature of 230 K from a harmonic to an anharmonic regime, provided the hydration of the membranes is sufficient. We found this onset of large amplitude motions correlated with the appearance of protein function under certain conditions of temperature and relative humidity.
AB - The internal motions of bacteriorhodopsin, the integral membrane protein in purple membranes of Halobacterium halobium, have been studied by neutron scattering as a function of different external conditions. The internal dynamics exhibit a transition above a critical temperature of 230 K from a harmonic to an anharmonic regime, provided the hydration of the membranes is sufficient. We found this onset of large amplitude motions correlated with the appearance of protein function under certain conditions of temperature and relative humidity.
UR - http://www.scopus.com/inward/record.url?scp=0013319758&partnerID=8YFLogxK
U2 - 10.1016/0378-4371(93)90445-A
DO - 10.1016/0378-4371(93)90445-A
M3 - Article
AN - SCOPUS:0013319758
SN - 0378-4371
VL - 201
SP - 425
EP - 429
JO - Physica A: Statistical Mechanics and its Applications
JF - Physica A: Statistical Mechanics and its Applications
IS - 1-3
ER -