@inproceedings{af6b1197083e4ce8b03fac897c3e0dfa,
title = "Dynamic multi-scale modeling of lung parenchyma",
abstract = "We present computational approaches for modeling lung parenchyma against the background of acute lung diseases and mechanical ventilation. An ensemble of alveoli representing a single ventilatory unit is modeled considering not only soft tissue behavior but also the influence of the covering surfactant lining. Novel nested multi-scale procedures are then employed to simulate the dynamic behavior of lung parenchyma as a whole and local alveolar ensembles simultaneously. A coupling of this multi-scale parenchyma model with a previously developed fluid-structure interaction model of the lower airways is proposed, opening up new vistas towards an overall {"}virtual{"} lung.",
keywords = "Biomechanics, Fluid-structure interaction, Interfacial phenomena, Multi-scale methods, Tissue mechanics",
author = "Lena Wiechert and Wall, \{Wolfgang A.\}",
year = "2009",
language = "English",
isbn = "9788496736696",
series = "Computational Plasticity X - Fundamentals and Applications",
booktitle = "Computational Plasticity X - Fundamentals and Applications",
note = "10th International Conference on Computational Plasticity, COMPLAS X ; Conference date: 02-09-2009 Through 04-09-2009",
}