TY - JOUR
T1 - Dynamic control of auxin transport-dependent growth by AGCVIII protein kinases
AU - Barbosa, Inês C.R.
AU - Schwechheimer, Claus
N1 - Publisher Copyright:
© 2014 Elsevier Ltd.
PY - 2014
Y1 - 2014
N2 - Recent years have seen important advances in understanding the Arabidopsis thaliana AGCVIII protein kinases D6 PROTEIN KINASE, PINOID/WAGs, and the phototropins. It has become apparent that these kinases control the distribution of the phytohormone auxin within the plant through phosphorylation of PIN-FORMED efflux carriers or of ABC transporters. Strikingly, D6PK and PID share the same phosphosites in PIN-FORMED proteins but have differential phosphosite preferences, which appear to control the activity and polar distribution of PIN-FORMED transporters. All three AGCVIII kinases are membrane-associated proteins that are dynamically transported to and from the plasma membrane. The implications of this dynamic transport for the activity and cell biological behavior of their phosphorylation substrates are just now starting to be understood.
AB - Recent years have seen important advances in understanding the Arabidopsis thaliana AGCVIII protein kinases D6 PROTEIN KINASE, PINOID/WAGs, and the phototropins. It has become apparent that these kinases control the distribution of the phytohormone auxin within the plant through phosphorylation of PIN-FORMED efflux carriers or of ABC transporters. Strikingly, D6PK and PID share the same phosphosites in PIN-FORMED proteins but have differential phosphosite preferences, which appear to control the activity and polar distribution of PIN-FORMED transporters. All three AGCVIII kinases are membrane-associated proteins that are dynamically transported to and from the plasma membrane. The implications of this dynamic transport for the activity and cell biological behavior of their phosphorylation substrates are just now starting to be understood.
UR - http://www.scopus.com/inward/record.url?scp=84955586439&partnerID=8YFLogxK
U2 - 10.1016/j.pbi.2014.09.010
DO - 10.1016/j.pbi.2014.09.010
M3 - Review article
C2 - 25305415
AN - SCOPUS:84955586439
SN - 1369-5266
VL - 22
SP - 108
JO - Current Opinion in Plant Biology
JF - Current Opinion in Plant Biology
ER -