Dopamine and adult neurogenesis

Andreas Borta; Günter U. Höglinger

doi:10.1111/j.1471-4159.2006.04241.x

Dopamine and adult neurogenesis

Andreas Borta, Günter U. Höglinger

Philipps-Universität Marburg

Research output: Contribution to journal › Review article › peer-review

180 Scopus citations

Abstract

Dopamine is an important neurotransmitter implicated in the regulation of mood, motivation and movement. We have reviewed here recent data suggesting that dopamine, in addition to being a neurotransmitter, also plays a role in the regulation of endogenous neurogenesis in the adult mammalian brain. In addition, we approach a highly controversial question: can the adult human brain use neurogenesis to replace the dopaminergic neurones in the substantia nigra that are lost in Parkinson's disease?

Original language	English
Pages (from-to)	587-595
Number of pages	9
Journal	Journal of Neurochemistry
Volume	100
Issue number	3
DOIs	https://doi.org/10.1111/j.1471-4159.2006.04241.x
State	Published - Feb 2007
Externally published	Yes

Keywords

Adult neurogenesis
Dopamine
Parkinson's disease
Substantia nigra
Subventricular zone

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1471-4159.2006.04241.x

Cite this

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AB - Dopamine is an important neurotransmitter implicated in the regulation of mood, motivation and movement. We have reviewed here recent data suggesting that dopamine, in addition to being a neurotransmitter, also plays a role in the regulation of endogenous neurogenesis in the adult mammalian brain. In addition, we approach a highly controversial question: can the adult human brain use neurogenesis to replace the dopaminergic neurones in the substantia nigra that are lost in Parkinson's disease?

KW - Adult neurogenesis

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KW - Parkinson's disease

KW - Substantia nigra

KW - Subventricular zone

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Dopamine and adult neurogenesis

Abstract

Keywords

UN SDGs

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