Abstract
Three patients with hematologic relapse after bone marrow transplantation for chronic myelogenous leukemia were treated with interferon α and transfusion of viable donor buffy coat. All had complete hematologic and cytogenetic remission, which persisted 32 to 91 weeks after treatment. In two patients graft-versus-host disease developed and was treated by immunosuppression. These results are an example of adoptive immunotherapy without cytoreductive chemotherapy or radiotherapy in human chimeras.
| Original language | English |
|---|---|
| Pages (from-to) | 2462-2465 |
| Number of pages | 4 |
| Journal | Blood |
| Volume | 76 |
| Issue number | 12 |
| State | Published - 15 Dec 1990 |
| Externally published | Yes |
