Distance metric learning using graph convolutional networks: Application to functional brain networks

Sofia Ira Ktena, Sarah Parisot, Enzo Ferrante, Martin Rajchl, Matthew Lee, Ben Glocker, Daniel Rueckert

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

117 Scopus citations

Abstract

Evaluating similarity between graphs is of major importance in several computer vision and pattern recognition problems, where graph representations are often used to model objects or interactions between elements. The choice of a distance or similarity metric is, however, not trivial and can be highly dependent on the application at hand. In this work, we propose a novel metric learning method to evaluate distance between graphs that leverages the power of convolutional neural networks, while exploiting concepts from spectral graph theory to allow these operations on irregular graphs. We demonstrate the potential of our method in the field of connectomics, where neuronal pathways or functional connections between brain regions are commonly modelled as graphs. In this problem, the definition of an appropriate graph similarity function is critical to unveil patterns of disruptions associated with certain brain disorders. Experimental results on the ABIDE dataset show that our method can learn a graph similarity metric tailored for a clinical application, improving the performance of a simple k-nn classifier by 11.9% compared to a traditional distance metric.

Original languageEnglish
Title of host publicationMedical Image Computing and Computer Assisted Intervention − MICCAI 2017 - 20th International Conference, Proceedings
EditorsMaxime Descoteaux, Simon Duchesne, Alfred Franz, Pierre Jannin, D. Louis Collins, Lena Maier-Hein
PublisherSpringer Verlag
Pages469-477
Number of pages9
ISBN (Print)9783319661810
DOIs
StatePublished - 2017
Externally publishedYes
Event20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017 - Quebec City, Canada
Duration: 11 Sep 201713 Sep 2017

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume10433 LNCS
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference20th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2017
Country/TerritoryCanada
CityQuebec City
Period11/09/1713/09/17

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