Discrimination of lymph node metastases using desorption electrospray ionisation-mass spectrometry imaging

N. Abbassi-Ghadi, K. Veselkov, S. Kumar, J. Huang, E. Jones, N. Strittmatter, H. Kudo, R. Goldin, Z. Takáts, G. B. Hanna

Research output: Contribution to journalArticlepeer-review

44 Scopus citations

Abstract

Desorption electrospray ionisation mass spectrometry imaging (DESI-MSI) has been used for the identification of cancer within lymph nodes with accurate spatial distribution in comparison to gold standard matched immuno-histopathological images. The metabolic profile of the cancerous lymph nodes was similar to that of the primary tumour site.

Original languageEnglish
Pages (from-to)3661-3664
Number of pages4
JournalChemical Communications
Volume50
Issue number28
DOIs
StatePublished - 11 Mar 2014
Externally publishedYes

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