Abstract
Background: Blood-brain barrier disruption as assessed with magnetic resonance imaging is not a reliable sign of gliomas. Positron emission tomography (PET) can be used to measure the transport of amino acids into tumor tissue, independent of the blood-brain barrier. Objective: This article reviews selected literature about the role of PET in gliomas. Methods: A search for relevant literature was carried out in PubMed. Results: In a concise manner this review explains the basic principles and procedures of amino acid PET. Clinical indications cover differentiation of benign findings, glioma delineation, grading, treatment planning and response, as well as differentiation between relapse and treatment-related changes. Conclusion: PET with radiolabeled amino acids represents a valuable additional tool for the diagnostics and treatment monitoring of gliomas.
| Translated title of the contribution | The role of positron emission tomography in gliomas |
|---|---|
| Original language | German |
| Pages (from-to) | 31-36 |
| Number of pages | 6 |
| Journal | Onkologe |
| Volume | 25 |
| Issue number | 1 |
| DOIs | |
| State | Published - 1 Jan 2019 |