TY - JOUR
T1 - Die Leishmaniasis - eine parasitäre Erkrankung als Differenzialdiagnose maligner Mundschleimhauterkrankungen. Fallbericht und Literaturübersicht
AU - Wysluch, Andreas
AU - Sommerer, Florian
AU - Ramadan, Hamid
AU - Loeffelbein, Denys
AU - Wolff, Klaus Dietrich
AU - Hölzle, Frank
PY - 2007/8
Y1 - 2007/8
N2 - Although parasitel infections in northern Europe are rare, it must be considered as differential diagnosis of malignant tumours of mucous membrane. With increasing tourisms in endemic areas, infections with parasite pathogen are spreading in non-endemic areas as well. In this case a mucous membrane malignancy with clinical feature of ulcer on unusual location was imitated. In this reported case the patient suffers with hepatitis c, causing cirrhosis of the liver and making a liver transplantation necessary. In this patient a history of a leishmaniosis which had been treated successful by the tropical institute is reported, but because of a new actually leishmaniosis-infection a liver transplantation is contraindicated. Under oral therapy with Miltefosin (IMPADIVO™) a remission was successful. The leishmaniosis is a classical tropical disease. WHO reported a morbidity of nearly 12 million people in 88 countries around the world especially in tropical areas. Repeatedly infections in northern Europe caused by the phlebotonus-sandflies are described. Therefore leishmaniosis must be considered as differential diagnosis in suspect lesions of mucous membrane.
AB - Although parasitel infections in northern Europe are rare, it must be considered as differential diagnosis of malignant tumours of mucous membrane. With increasing tourisms in endemic areas, infections with parasite pathogen are spreading in non-endemic areas as well. In this case a mucous membrane malignancy with clinical feature of ulcer on unusual location was imitated. In this reported case the patient suffers with hepatitis c, causing cirrhosis of the liver and making a liver transplantation necessary. In this patient a history of a leishmaniosis which had been treated successful by the tropical institute is reported, but because of a new actually leishmaniosis-infection a liver transplantation is contraindicated. Under oral therapy with Miltefosin (IMPADIVO™) a remission was successful. The leishmaniosis is a classical tropical disease. WHO reported a morbidity of nearly 12 million people in 88 countries around the world especially in tropical areas. Repeatedly infections in northern Europe caused by the phlebotonus-sandflies are described. Therefore leishmaniosis must be considered as differential diagnosis in suspect lesions of mucous membrane.
KW - Differential diagnosis of squamous cell carcinoma
KW - Leishmaniosis
KW - Miltefosin
KW - Mucous membrane disease
KW - Phlebotonus-sandflie
UR - http://www.scopus.com/inward/record.url?scp=34547824142&partnerID=8YFLogxK
U2 - 10.1007/s10006-007-0061-9
DO - 10.1007/s10006-007-0061-9
M3 - Artikel
C2 - 17566798
AN - SCOPUS:34547824142
SN - 1432-9417
VL - 11
SP - 167
EP - 173
JO - Mund-, Kiefer- und Gesichtschirurgie : MKG
JF - Mund-, Kiefer- und Gesichtschirurgie : MKG
IS - 3
ER -