Die intravenös stimulierte Insulinreserve des Pankreas nach experimenteller Pankreasgangligatur beim Schwein -Untersuchungen 2, 4 und etwa 60 Tage nach Ligatur

M. Berkhoff; D. Großner; R. Klapdor; G. Klöppel; H. v. Kroge

doi:10.1007/BF01274227

Die intravenös stimulierte Insulinreserve des Pankreas nach experimenteller Pankreasgangligatur beim Schwein -Untersuchungen 2, 4 und etwa 60 Tage nach Ligatur

Translated title of the contribution: Intravenously stimulated insulin reserve of the pancreas following experimental pancreatic duct ligation in pigs - investigations 2, 4 and 60 days after ligation

M. Berkhoff, D. Großner, R. Klapdor, G. Klöppel, H. v. Kroge

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

After pancreatic duct ligation (PDL) intravenous glucose tolerance tests (i.v. GTT) were performed in 12 pigs. The release of insulin and the corresponding blood sugar levels were controlled, the pancreata were examined histologically and immunhistochemically. In spite of a reduced number of β-cells no reduction of glucose tolerance could be shown 60 days after PDL. Two days after the i.v. GTT showed an increased release of insulin corresponding with lowered blood sugar levels. This phenomenon is explained as a stimulated state of the β-cell in the phase of interstitial edema.

Translated title of the contribution	Intravenously stimulated insulin reserve of the pancreas following experimental pancreatic duct ligation in pigs - investigations 2, 4 and 60 days after ligation
Original language	German
Pages (from-to)	151-158
Number of pages	8
Journal	Langenbecks Archiv für Chirurgie
Volume	373
Issue number	3
DOIs	https://doi.org/10.1007/BF01274227
State	Published - May 1988
Externally published	Yes

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title = "Die intraven{\"o}s stimulierte Insulinreserve des Pankreas nach experimenteller Pankreasgangligatur beim Schwein -Untersuchungen 2, 4 und etwa 60 Tage nach Ligatur",

abstract = "After pancreatic duct ligation (PDL) intravenous glucose tolerance tests (i.v. GTT) were performed in 12 pigs. The release of insulin and the corresponding blood sugar levels were controlled, the pancreata were examined histologically and immunhistochemically. In spite of a reduced number of β-cells no reduction of glucose tolerance could be shown 60 days after PDL. Two days after the i.v. GTT showed an increased release of insulin corresponding with lowered blood sugar levels. This phenomenon is explained as a stimulated state of the β-cell in the phase of interstitial edema.",

keywords = "Endocrine pancreas, Pancreatic duct ligation, i. v. insulin reserve",

author = "M. Berkhoff and D. Gro{\ss}ner and R. Klapdor and G. Kl{\"o}ppel and Kroge, {H. v.}",

year = "1988",

month = may,

doi = "10.1007/BF01274227",

language = "Deutsch",

volume = "373",

pages = "151--158",

journal = "Langenbecks Archiv f{\"u}r Chirurgie",

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publisher = "Springer Verlag",

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T1 - Die intravenös stimulierte Insulinreserve des Pankreas nach experimenteller Pankreasgangligatur beim Schwein -Untersuchungen 2, 4 und etwa 60 Tage nach Ligatur

AU - Berkhoff, M.

AU - Großner, D.

AU - Klapdor, R.

AU - Klöppel, G.

AU - Kroge, H. v.

PY - 1988/5

Y1 - 1988/5

N2 - After pancreatic duct ligation (PDL) intravenous glucose tolerance tests (i.v. GTT) were performed in 12 pigs. The release of insulin and the corresponding blood sugar levels were controlled, the pancreata were examined histologically and immunhistochemically. In spite of a reduced number of β-cells no reduction of glucose tolerance could be shown 60 days after PDL. Two days after the i.v. GTT showed an increased release of insulin corresponding with lowered blood sugar levels. This phenomenon is explained as a stimulated state of the β-cell in the phase of interstitial edema.

AB - After pancreatic duct ligation (PDL) intravenous glucose tolerance tests (i.v. GTT) were performed in 12 pigs. The release of insulin and the corresponding blood sugar levels were controlled, the pancreata were examined histologically and immunhistochemically. In spite of a reduced number of β-cells no reduction of glucose tolerance could be shown 60 days after PDL. Two days after the i.v. GTT showed an increased release of insulin corresponding with lowered blood sugar levels. This phenomenon is explained as a stimulated state of the β-cell in the phase of interstitial edema.

KW - Endocrine pancreas

KW - Pancreatic duct ligation

KW - i. v. insulin reserve

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U2 - 10.1007/BF01274227

DO - 10.1007/BF01274227

M3 - Artikel

C2 - 3288828

AN - SCOPUS:0023819643

SN - 0023-8236

VL - 373

SP - 151

EP - 158

JO - Langenbecks Archiv für Chirurgie

JF - Langenbecks Archiv für Chirurgie

IS - 3

ER -

Die intravenös stimulierte Insulinreserve des Pankreas nach experimenteller Pankreasgangligatur beim Schwein -Untersuchungen 2, 4 und etwa 60 Tage nach Ligatur

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