Abstract
All colloidal volume substitutes carry the risk of anaphylactoid reactions. The general incidence of 0.03% is low; however severe complications can occur. There are different pathomechanisms involved in the induction of anaphylactoid reactions after infusion of different colloids. Protein aggregates are of pathogenic importance in human serum albumin incompatibility. The addition of stabilizers to the plasma protein solutions can alter the immunogenicity of the protein molecule. Antibodies of the classes IgG and IgM seem to play a role in severe dextran incompatibility. There was a direct correlation of the intensity of the clinical symptoms with the anti dextran antibody titer.
| Translated title of the contribution | The anaphylactoid reaction after colloid infusion |
|---|---|
| Original language | German |
| Pages (from-to) | 2481-2486 |
| Number of pages | 6 |
| Journal | Fortschritte der Medizin |
| Volume | 95 |
| Issue number | 41 |
| State | Published - 1977 |
| Externally published | Yes |