Diagnostic agents

Knut Brockow

doi:10.1007/978-3-030-82743-4_31

Diagnostic agents

Knut Brockow

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Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

Hypersensitivity to diagnostic agents may be caused by allergic and nonallergic mechanisms. Immediate hypersensitivity reactions (IHRs) with anaphylaxis are common to iodinated radiocontrast media (RCM), gadolinium-based contrast agents, and blue dyes. In some patients, an immediate-type allergy can be demonstrated by skin test and basophil activation test. Drug provocation tests can be done to confirm tolerability of skin test-negative alternatives. Non-immediate hypersensitivity reactions (NIHRs) to RCM present with exanthemas and are mostly skin test-positive T-cell-mediated hypersensitivity reactions.

Original language	English
Title of host publication	Cutaneous Drug Hypersensitivity
Subtitle of host publication	Clinical Features, Mechanisms, Diagnosis, and Management
Publisher	Springer International Publishing
Pages	273-278
Number of pages	6
ISBN (Electronic)	9783030827434
ISBN (Print)	9783030827427
DOIs	https://doi.org/10.1007/978-3-030-82743-4_31
State	Published - 9 Jul 2022

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10.1007/978-3-030-82743-4_31

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ER -

Diagnostic agents

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