Abstract
Numerous illnesses progress silently, often reaching a critical stage by the time symptoms appear, making medical intervention difficult. While there exist sophisticated clinical techniques for precise disease detection, they are often invasive procedure and as a rule of thumb is used only with definite symptomatic cases. In addition, the extreme clinical costs prevent a large population from taking advantage of contemporary medical facilities. A non-invasive, economically feasible screening method that detects diseases even in their pre-symptomatic stages may overcome many critical challenges in health and medicine. Utilizing vibrational spectroscopy to identify volatile metabolites offers promise as such a non-invasive, cost-effective diagnostic tool. The article outlines the potential of vibrational spectroscopy for non-invasive diagnostics and proposes a method for its clinical implementation.
Original language | English |
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Article number | 103724 |
Journal | Vibrational Spectroscopy |
Volume | 134 |
DOIs | |
State | Published - Sep 2024 |
Keywords
- Clinical statistics
- Component analysis
- Gaseas biofluids
- Metabolites
- Non-invasive diagnosis
- Vibrational spectroscopy
- Volatile organic compounds (VOCs)