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Development of an active agent carrying, biodegradable implant for the intravesical therapy of the overactive bladder syndrome

  • RWTH Aachen University
  • University Hospital
  • Department and Chair for Medical Engineering

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

1 Scopus citations

Abstract

The overactive bladder syndrome (OAB) is defined as a symptom complex which is characterized with frequent urination, urinary incontinence and a strong, sudden urge to urinate even when the bladder is not full. About 10% of the total population have OAB and it occurs in every age group. Apart from the medical, oral therapy, the so called intravesical instillation is used as well. In order to minimise the numerous side effects of the oral therapy like dry mouth, dizziness or depressions a biodegradable, active agent carrying implant for the intravesical therapy of the OAB was aspired. After a project period of two years a biodegradable, active agent carrying polymer implant could be developed.

Original languageEnglish
Title of host publication67th Annual Technical Conference of the Society of Plastics Engineers 2009, ANTEC 2009
Pages2951-2956
Number of pages6
StatePublished - 2009
Externally publishedYes
Event67th Annual Technical Conference of the Society of Plastics Engineers 2009, ANTEC 2009 - Chicago, IL, United States
Duration: 22 Jun 200924 Jun 2009

Publication series

NameAnnual Technical Conference - ANTEC, Conference Proceedings
Volume5

Conference

Conference67th Annual Technical Conference of the Society of Plastics Engineers 2009, ANTEC 2009
Country/TerritoryUnited States
CityChicago, IL
Period22/06/0924/06/09

Keywords

  • Biodegradable polymers
  • CESP-process
  • Drug-release
  • Electrospinning
  • Overactive bladder

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