Deuteration of Hyperpolarized 13C-Labeled Zymonic Acid Enables Sensitivity-Enhanced Dynamic MRI of pH

Christian Hundshammer; Stephan Düwel; Simone S. Köcher; Malte Gersch; Benedikt Feuerecker; Christoph Scheurer; Axel Haase; Steffen J. Glaser; Markus Schwaiger; Franz Schilling

doi:10.1002/cphc.201700956

Deuteration of Hyperpolarized ¹³C-Labeled Zymonic Acid Enables Sensitivity-Enhanced Dynamic MRI of pH

Christian Hundshammer, Stephan Düwel, Simone S. Köcher, Malte Gersch, Benedikt Feuerecker, Christoph Scheurer, Axel Haase, Steffen J. Glaser, Markus Schwaiger, Franz Schilling

Research output: Contribution to journal › Comment/debate

Abstract

The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH-sensitive ¹³C NMR resonances and examples of how this sensor can be used to non-invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779.

Original language	English
Pages (from-to)	2421
Number of pages	1
Journal	ChemPhysChem
Volume	18
Issue number	18
DOIs	https://doi.org/10.1002/cphc.201700956
State	Published - 20 Sep 2017

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title = "Deuteration of Hyperpolarized 13C-Labeled Zymonic Acid Enables Sensitivity-Enhanced Dynamic MRI of pH",

abstract = "The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH-sensitive 13C NMR resonances and examples of how this sensor can be used to non-invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779.",

author = "Christian Hundshammer and Stephan D{\"u}wel and K{\"o}cher, {Simone S.} and Malte Gersch and Benedikt Feuerecker and Christoph Scheurer and Axel Haase and Glaser, {Steffen J.} and Markus Schwaiger and Franz Schilling",

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AU - Hundshammer, Christian

AU - Düwel, Stephan

AU - Köcher, Simone S.

AU - Gersch, Malte

AU - Feuerecker, Benedikt

AU - Scheurer, Christoph

AU - Haase, Axel

AU - Glaser, Steffen J.

AU - Schwaiger, Markus

AU - Schilling, Franz

PY - 2017/9/20

Y1 - 2017/9/20

N2 - The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH-sensitive 13C NMR resonances and examples of how this sensor can be used to non-invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779.

AB - The front cover artwork is provided by the groups of Dr. Christoph Scheurer, Prof. Axel Haase, Prof. Steffen J. Glaser, Prof. Markus Schwaiger and Dr. Franz Schilling from Technical University of Munich. The image shows deuterated zymonic acid, its pH-sensitive 13C NMR resonances and examples of how this sensor can be used to non-invasively image pH both in vitro and in vivo. Read the full text of the article at 10.1002/cphc.201700779.

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M3 - Comment/debate

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SP - 2421

JO - ChemPhysChem

JF - ChemPhysChem

IS - 18

ER -

Deuteration of Hyperpolarized ¹³C-Labeled Zymonic Acid Enables Sensitivity-Enhanced Dynamic MRI of pH

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