Determination of the ϕ angle in a peptide backbone by NMR spectroscopy with a combination of homonuclear and heteronuclear coupling constants

Peter Schmieder, Horst Kessler

Research output: Contribution to journalArticlepeer-review

31 Scopus citations

Abstract

The ϕ angle in a cyclic peptide is determined by the combined use of homonuclear and heteronuclear coupling constants. Two of the four coupling constants that define the ϕ angle in a peptide are determined exactly, two qualitatively. Via Karplus‐type equations, they are transformed into dihedral angles and a good agreement is found, allowing for a determination of the ϕ angle with a certain range of degrees.

Original languageEnglish
Pages (from-to)435-440
Number of pages6
JournalBiopolymers
Volume32
Issue number4
DOIs
StatePublished - Apr 1992
Externally publishedYes

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