Abstract
A method for quantitative determination of cross-relaxation rates of macromolecules in solution is developed. The method is based on the analysis of the intensities of cross peaks in 3D NOE-NOE spectra. The linear combination of the intensities of 3D peaks (spin-diffusion peaks, back-transfer peaks) results in an expression directly proportional to the cross-relaxation rate. The proposed approach allows to determine interproton distances in macromolecules more accurately.
| Original language | English |
|---|---|
| Pages (from-to) | 83-92 |
| Number of pages | 10 |
| Journal | Journal of Biomolecular NMR |
| Volume | 1 |
| Issue number | 1 |
| DOIs | |
| State | Published - May 1991 |
Keywords
- 3D NOE-NOE spectroscopy
- Cross-relaxation rales
- Interproton distances
- Macromolecules
- Spin diffusion