Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

F. Salami; M. Abels; H. Hyöty; F. Vaziri-Sani; C. A. Aronsson; K. Vehik; A. Delli; W. A. Hagopian; M. Rewers; A. G. Ziegler; O. Simell; B. Akolkar; J. Krischer; J. She; Å Leramark

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

F. Salami
, M. Abels
, H. Hyöty
, F. Vaziri-Sani
, C. A. Aronsson
, K. Vehik
, A. Delli
, W. A. Hagopian
, M. Rewers
, A. G. Ziegler
, O. Simell
, B. Akolkar
, J. Krischer
, J. She
, Å Leramark

Department of Pediatric Medicine

Lund University
Tampere University Hospital
University of South Florida College of Medicine
Pacific Northwest Diabetes Research Institute
Barbara Davis Center for Childhood Diabetes
University of Turku and Turku University Hospital
National Institutes of Health
Medical College of Georgia

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.

Original language	English
Pages (from-to)	135-144
Number of pages	10
Journal	International Journal of Probiotics and Prebiotics
Volume	7
Issue number	3-4
State	Published - 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Autoimmune diabetes
Celiac disease
Infants
Microflora
Probiotics

Cite this

Salami, F., Abels, M., Hyöty, H., Vaziri-Sani, F., Aronsson, C. A., Vehik, K., Delli, A., Hagopian, W. A., Rewers, M., Ziegler, A. G., Simell, O., Akolkar, B., Krischer, J., She, J., & Leramark, Å. (2012). Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes. International Journal of Probiotics and Prebiotics, 7(3-4), 135-144.

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title = "Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes",

abstract = "The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.",

keywords = "Autoimmune diabetes, Celiac disease, Infants, Microflora, Probiotics",

author = "F. Salami and M. Abels and H. Hy{\"o}ty and F. Vaziri-Sani and Aronsson, \{C. A.\} and K. Vehik and A. Delli and Hagopian, \{W. A.\} and M. Rewers and Ziegler, \{A. G.\} and O. Simell and B. Akolkar and J. Krischer and J. She and {\AA} Leramark",

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Salami, F, Abels, M, Hyöty, H, Vaziri-Sani, F, Aronsson, CA, Vehik, K, Delli, A, Hagopian, WA, Rewers, M, Ziegler, AG, Simell, O, Akolkar, B, Krischer, J, She, J & Leramark, Å 2012, 'Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes', International Journal of Probiotics and Prebiotics, vol. 7, no. 3-4, pp. 135-144.

TY - JOUR

T1 - Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

AU - Salami, F.

AU - Abels, M.

AU - Hyöty, H.

AU - Vaziri-Sani, F.

AU - Aronsson, C. A.

AU - Vehik, K.

AU - Delli, A.

AU - Hagopian, W. A.

AU - Rewers, M.

AU - Ziegler, A. G.

AU - Simell, O.

AU - Akolkar, B.

AU - Krischer, J.

AU - She, J.

AU - Leramark, Å

PY - 2012

Y1 - 2012

N2 - The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.

AB - The feasibility to detect lactobacilli in mail-in infant stools collected monthly from 3-18 months old children was investigated. The aim was to determine total lactobacilli and Lactobacillus plantarum (L. plantarum) content (ng/g feces) in 50 infants each from Colorado (648 samples), Finland (624 samples) and Sweden (685 samples) who participated in the TEDDY (The Environmental Determinants of Diabetes in the Young) study. Total lactobacilli content varied markedly between 5 and 16,800 ng/g feces in the three clinical sites within and between individuals especially in infants. L.plantarum also varied markedly intra- and interindividually from <0.5-736 ng/g feces. A higher variability of total lactobacilli was found before 10 months of age than after in the three different clinical sites. Sweden had the lowest total lactobacilli content compared to Colorado and Finland while the L.plantarum content was higher in Sweden. Mailin stool samples from infants should prove useful in analyzing probiotics in childhood.

KW - Autoimmune diabetes

KW - Celiac disease

KW - Infants

KW - Microflora

KW - Probiotics

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M3 - Article

AN - SCOPUS:84886941311

SN - 1555-1431

VL - 7

SP - 135

EP - 144

JO - International Journal of Probiotics and Prebiotics

JF - International Journal of Probiotics and Prebiotics

IS - 3-4

ER -

Detection of lactobacilli in monthly mail-in stool samples from 3-18 months old infants at genetic risk for type 1 diabetes

Abstract

UN SDGs

Keywords

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