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Detecting the onset of myocardial contraction for establishing inverse electro-mechanical coupling in XMR guided RF ablation

  • Gerardo I. Sanchez-Ortiz
  • , Maxime Sermesant
  • , Raghavendra Chandrashekara
  • , Kawal S. Rhode
  • , Reza Razavi
  • , Derek L.G. Hill
  • , Daniel Rueckert
  • Imperial College London
  • King's College London School of Medicine

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

7 Scopus citations

Abstract

Radio-frequency (RF) ablation uses electrode-catheters to destroy abnormally conducting myocardial areas that lead to potentially lethal tachyarrhythmias. The procedure is normally guided with x-rays (2D), leading to errors in location and excessive radiation exposure. In order to provide pre- and intra-operative 3D MR guidance, we define a probabilistic measure of regional motion activation. Non-rigid registration of tagged MR sequences is used to track heart motion. Regional motion is also compared between different acquisitions, thus assisting in diagnosing arrhythmia, in follow up of treatment, and in determining whether ablation succeeded. We validate using an electro-mechanical model, synthetic tagged MRI, stress data on healthy volunteers, and one patient with tachyarrhythmia, before and after ablation.

Original languageEnglish
Title of host publication2004 2nd IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationMacro to Nano
PublisherInstitute of Electrical and Electronics Engineers Inc.
Pages1055-1058
Number of pages4
ISBN (Print)0780383885, 9780780383883
DOIs
StatePublished - 2004
Externally publishedYes
Event2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, ISBI 2004 - Arlington, VA, United States
Duration: 18 Apr 200418 Apr 2004

Publication series

Name2004 2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano
Volume2

Conference

Conference2nd IEEE International Symposium on Biomedical Imaging: Macro to Nano, ISBI 2004
Country/TerritoryUnited States
CityArlington, VA
Period18/04/0418/04/04

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