@inproceedings{7085bc08405340558148b7dccb8681b8,
title = "DESIGNE AND IMPLEMENTATION OF BIOHYBRID DIAPHRAGM PUMP TO BE DRIVEN BY CARDIO MYOCYTES",
abstract = "In this report we introduce the design and prototype implementation of a bio hybrid pump driven by cardiac muscle tissue to supply other biological actuators in a larger bio hybrid robotic system sufficiently with nutrition media. Recently introduced bio hybrid pumps are analyzed and compared. On this basis a diaphragm pump design is chosen as physical principal and a functional prototype is designed. The derived requirements regarding the flowrates and long-term stability are verified with mechanical tests of the implemented prototype. The pump itself will consist of a body, an actuating membrane (to carry future muscle cells), a cylindrical spacer block, a returning diaphragm and the retaining ring. During operation the flow direction is implemented by two check valves. Our mechanical verification results show a flowrate of 14.2 ml/min with an activation frequency of 1 Hz. For the displacement of the returning diaphragm a required force of 0.58 N is determined. This is well within the capabilities of cardio myocytes which are in the range of 2 to 5 nN/μm2 and therefore could generate 0.63 to 1.57 N given the area of the 40 mm diameter membrane.",
keywords = "bio hybrid pump, bio hybrid robotics, cardio myocytes, diaphragm, high flow rate",
author = "Lucas Artmann and Valentin Ameres and Emmy Wund and Lueth, {Tim C.}",
note = "Publisher Copyright: Copyright {\textcopyright} 2022 by ASME.; ASME 2022 International Mechanical Engineering Congress and Exposition, IMECE 2022 ; Conference date: 30-10-2022 Through 03-11-2022",
year = "2022",
doi = "10.1115/IMECE2022-94399",
language = "English",
series = "ASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)",
publisher = "American Society of Mechanical Engineers (ASME)",
booktitle = "Biomedical and Biotechnology; Design, Systems, and Complexity",
}