DESIGNE AND IMPLEMENTATION OF BIOHYBRID DIAPHRAGM PUMP TO BE DRIVEN BY CARDIO MYOCYTES

Lucas Artmann, Valentin Ameres, Emmy Wund, Tim C. Lueth

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

In this report we introduce the design and prototype implementation of a bio hybrid pump driven by cardiac muscle tissue to supply other biological actuators in a larger bio hybrid robotic system sufficiently with nutrition media. Recently introduced bio hybrid pumps are analyzed and compared. On this basis a diaphragm pump design is chosen as physical principal and a functional prototype is designed. The derived requirements regarding the flowrates and long-term stability are verified with mechanical tests of the implemented prototype. The pump itself will consist of a body, an actuating membrane (to carry future muscle cells), a cylindrical spacer block, a returning diaphragm and the retaining ring. During operation the flow direction is implemented by two check valves. Our mechanical verification results show a flowrate of 14.2 ml/min with an activation frequency of 1 Hz. For the displacement of the returning diaphragm a required force of 0.58 N is determined. This is well within the capabilities of cardio myocytes which are in the range of 2 to 5 nN/μm2 and therefore could generate 0.63 to 1.57 N given the area of the 40 mm diameter membrane.

Original languageEnglish
Title of host publicationBiomedical and Biotechnology; Design, Systems, and Complexity
PublisherAmerican Society of Mechanical Engineers (ASME)
ISBN (Electronic)9780791886663
DOIs
StatePublished - 2022
EventASME 2022 International Mechanical Engineering Congress and Exposition, IMECE 2022 - Columbus, United States
Duration: 30 Oct 20223 Nov 2022

Publication series

NameASME International Mechanical Engineering Congress and Exposition, Proceedings (IMECE)
Volume4

Conference

ConferenceASME 2022 International Mechanical Engineering Congress and Exposition, IMECE 2022
Country/TerritoryUnited States
CityColumbus
Period30/10/223/11/22

Keywords

  • bio hybrid pump
  • bio hybrid robotics
  • cardio myocytes
  • diaphragm
  • high flow rate

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