Dermatologic adverse events caused by biologic treatments – Pathogenesis and management

Laura Katharina Trefzer, Anna Caroline Pilz, Kilian Eyerich

Research output: Contribution to journalArticlepeer-review

Abstract

Biologics are approved for various dermatologic, allergic, rheumatic, and gastroenterologic inflammatory diseases, as well as for numerous malignancies. The dermatologic adverse events from treatment with biologics may resemble primary inflammatory diseases but differ in pathogenesis. In this article, we describe five different pathogenic mechanisms of dermatologic adverse events. By studying these mechanisms, we hope to gain valuable insights into the pathogenesis of primary inflammatory diseases. In addition, in this article, we provide recommendations for the treatment and management of the dermatological adverse events induced by biologics.

Original languageEnglish
Pages (from-to)1126-1136
Number of pages11
JournalJDDG - Journal of the German Society of Dermatology
Volume22
Issue number8
DOIs
StatePublished - Aug 2024

Keywords

  • adverse events
  • biologics
  • injection reaction
  • paradox psoriasis
  • vaccination

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