Abstract
Myocardial Infarction in a first-degree relative is an established cardiovascular risk factor. Twin and family studies revealed an estimate for heritability (h2) of up to 60 % for Myocardial Infarction. Major cardiovascular risk factors including hypercholesterinemia, hypertension and diabetes mellitus are also in part genetically determined. Several genomic variants have been identified that increase the risk for cardiovascular diseases. Genome wide association studies identified further common risk alleles that contribute to the manifestation of coronary artery disease, many by yet unknown mechanisms.
| Translated title of the contribution | Heart infarction genetics: Long way from positive family history to the gene |
|---|---|
| Original language | German |
| Pages (from-to) | 288-295 |
| Number of pages | 8 |
| Journal | Chemie in Unserer Zeit |
| Volume | 43 |
| Issue number | 5 |
| DOIs | |
| State | Published - Oct 2009 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
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