Der einfluss palliativer strahlentherapie auf schmerz und lebensqualität bei patienten mit knochenmetastasen

Translated title of the contribution: Pain and quality of life following palliative radiotherapy of bone metastases

Nina Sauer, Daniel Leising, Beate Wild, Martina Treiber, Peter Henningsen, Thorsten Jakobsen

Research output: Contribution to journalArticlepeer-review

8 Scopus citations

Abstract

Background and Purpose: Palliative irradiation is used to provide pain relief and to increase quality of life. Most studies exclude patients with advanced cancer disease and, therefore, a positive selection results. This prospective clinical study investigates the effect of palliative radiotherapy on pain and quality of life of patients with painful bone metastases. Patients and Methods: 263 patients with bone metastases due to advanced cancer were observed with respect to pain and quality of life during a 2-month course of radiotherapy. Missing data were substituted by the LOCF method (last observation carried forward) to prevent a biased reduction of data. Results: Radiotherapy resulted in pain relief. In the complete group, pain medication was not increased. Quality of life was not affected positively. Side effects of radiotherapy increased remarkably. Conclusion: Radiotherapy leads to pain relief. However, risks and benefits must be considered critically due to side effects.

Translated title of the contributionPain and quality of life following palliative radiotherapy of bone metastases
Original languageGerman
Pages (from-to)550-556
Number of pages7
JournalStrahlentherapie und Onkologie
Volume182
Issue number9
DOIs
StatePublished - Sep 2006
Externally publishedYes

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