Abstract
A semiempirical method for the inversion of photoacoustic signal profiles is presented, which allows the depth-resolved determination of the absorption coefficient of nonscattering samples. Experimentally determined reference profiles were used to reconstruct photoacoustic signal profiles measured with an indirect photoacoustic sensor system. The system was calibrated with homogeneous hydrogel samples. The developed inversion method was applied to layered hydrogel samples (two or three layers) and to a sample with continuously varying absorption properties. Particularly the investigation of the latter sample showed that the depth resolution of the used photoacoustic detection system is about 10 μm.
| Original language | English |
|---|---|
| Pages (from-to) | 4663-4668 |
| Number of pages | 6 |
| Journal | Analytical Chemistry |
| Volume | 71 |
| Issue number | 20 |
| DOIs | |
| State | Published - 15 Oct 1999 |