Keyphrases
Kinase Activity
100%
Pyruvate Kinase
100%
Glycolytic Intermediates
100%
Regulatory Axis
100%
Thioredoxin-interacting Protein (TXNIP)
100%
MondoA
33%
Reactive Oxygen Species
22%
Transcription Factor
22%
Histone Modification
22%
Metabolism
11%
Gene Expression
11%
Protein Level
11%
Tumor Suppressor
11%
Putative Drug Targets
11%
Key Rate
11%
Healthy Cells
11%
Cancer Cells
11%
Cellular Structure
11%
Anticancer Activity
11%
Lactate
11%
Oxidative Damage
11%
Knockdown
11%
Glucose-6-phosphatase (G6Pase)
11%
Cellular Processes
11%
Combination Chemotherapy
11%
Growth Advantage
11%
Epigenetic Targets
11%
Cancer Cell Lines
11%
Pro-tumorigenic
11%
Glycolytic Flux
11%
H3K4me3
11%
Transcriptional Targets
11%
Glycolytic Activity
11%
Metabolic Perturbation
11%
H3K9ac
11%
Metabolic Targets
11%
Perturbation Results
11%
Tumor Suppressor Activity
11%
Thioredoxin
11%
Protein Upregulation
11%
Rate-limiting Enzyme
11%
Biochemistry, Genetics and Molecular Biology
Thioredoxin
100%
Pyruvate Kinase
100%
Animal Model
22%
Histone Modification
22%
Cancer Cell
22%
Transcription Factors
22%
Metabolic Pathway
11%
Epigenetics
11%
Tumor Suppressor Protein
11%
Glucose 6-Phosphate
11%
Enzyme
11%
Reprogramming
11%
Gene Expression
11%
Antineoplastic Activity
11%
Upregulation
11%