Data independent acquisition mass spectrometry of irradiated mouse lung endothelial cells reveals a STAT-associated inflammatory response

Keyphrases

• Inflammatory Response 100%
• Lung Epithelial Cells 100%
• Mouse Lung 100%
• Data-independent Acquisition Mass Spectrometry (DIA-MS) 100%
• Radiation Effects 66%
• Interferon Regulatory Factor 3 (IRF3) 66%
• X-ray 33%
• Superoxide Dismutase 1 (SOD1) 33%
• Breast Cancer 33%
• Radiation Therapy 33%
• Adverse Consequences 33%
• Sham 33%
• Data-independent Acquisition 33%
• Induced Oxidative Stress 33%
• Stimulator of Interferon Genes (STING) 33%
• Immunoblotting 33%
• Dysregulated 33%
• Biological Pathways 33%
• Ingenuity Pathway Analysis 33%
• Active Form 33%
• Pulmonary Inflammation 33%
• CGAS-STING 33%
• Lung Inflammation 33%
• Radiation-induced Lung Injury 33%
• Upstream Regulator 33%
• Inflammatory Proteins 33%
• Interferon-stimulated Gene 15 (ISG15) 33%
• Quantitative Proteomic Analysis 33%
• Antioxidant Proteins 33%
• JAK-STAT 33%
• STING Pathway 33%
• Thorax Irradiation 33%
• Irradiated Sample 33%

Biochemistry, Genetics and Molecular Biology

• STAT1 100%
• Mass Spectrometry 100%
• IRF3 100%
• X Ray 50%
• ISG15 50%
• Oxidative Stress 50%
• SOD1 50%
• Quantitative Proteomics 50%
• Immunoblotting 50%
• cGAS-STING pathway 50%

Pharmacology, Toxicology and Pharmaceutical Science

• Interferon Regulatory Factor 3 100%
• Inflammation 100%
• Western Blot 50%
• Breast Cancer 50%
• Antioxidant 50%